Submission Type
Poster
Abstract
Calcium phosphate-based cements (CPCs) have been under investigation for use in setting and repairing bone fractures as a method to replace auto-grafting. Hydroxyapatite (HA) is a calcium phosphate mineral and the main mineral component of bone, making it a suitable basis for biocompatible cements. HA cements alone however lack mechanical strength and the porosity required for osteocyte ingrowth and proliferation. In this study, we examine the addition of a protein polymer collagen on the mechanical strength and pore structure of a HA-based CPC via measurements of shear strength and compressive strength, as well as scanning electron microscopy. The study is an ongoing investigation, and the data obtain thus far is presented and discussed.
Recommended Citation
Vincent, Owen, "251-Bone Fracture Repair: Analysis of Mechanical Strength and Porosity Properties of Biocompatible Collagen Cements" (2024). GREAT Day Posters. 71.
https://knightscholar.geneseo.edu/great-day-symposium/great-day-2024/posters-2024/71
251-Bone Fracture Repair: Analysis of Mechanical Strength and Porosity Properties of Biocompatible Collagen Cements
Calcium phosphate-based cements (CPCs) have been under investigation for use in setting and repairing bone fractures as a method to replace auto-grafting. Hydroxyapatite (HA) is a calcium phosphate mineral and the main mineral component of bone, making it a suitable basis for biocompatible cements. HA cements alone however lack mechanical strength and the porosity required for osteocyte ingrowth and proliferation. In this study, we examine the addition of a protein polymer collagen on the mechanical strength and pore structure of a HA-based CPC via measurements of shear strength and compressive strength, as well as scanning electron microscopy. The study is an ongoing investigation, and the data obtain thus far is presented and discussed.